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Departments

Department of Synthetic Biology and Immunology

Research of the molecular mechanism of molecular recognition and signaling in innate immune response, drug design and synthetic biology.

 

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Representative Publications

  1. LEBAR, Tina, LAINŠČEK, Duško, MERLJAK, Estera, AUPIČ, Jana, JERALA, Roman. A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cellsNature chemical biology, 2020.
  2. LEBAR, Tina, VERBIČ, Anže, LJUBETIČ, Ajasja, JERALA, Roman. Polarized displacement by transcription activator-like effectors for regulatory circuits. Nature chemical biology, 2019, 15, 80-87.
  3. FINK, Tina, LONZARIĆ, Jan, PRAZNIK, Arne, PLAPER, Tjaša, MERLJAK, Estera, LEBEN, Katja, JERALA, Nina, LEBAR, Tina, STRMŠEK, Žiga, LAPENTA, Fabio, BENČINA, Mojca, JERALA, Roman. Design of fast proteolysis-based signaling and logic circuits in mammalian cells. Nature chemical biology, 2018, 1-17.
  4. HAFNER BRATKOVIČ, Iva, SUŠJAN, Petra, LAINŠČEK, Duško, TAPIA-ABELLÁN, Ana, CEROVIĆ, Kosta, KADUNC, Lucija, ANGOSTO-BAZARRA, Diego, PELEGRIN, Pablo, JERALA, Roman. NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathwayNature communications, 2018, 9, 5182, 1-18.
  5. LJUBETIČ, Ajasja, LAPENTA, Fabio, GRADIŠAR, Helena, DROBNAK, Igor, AUPIČ, Jana, STRMŠEK, Žiga, LAINŠČEK, Duško, HAFNER-BRATKOVIČ, Iva,  MAJERLE, Andreja, KRIVEC, Nuša, BENČINA, Mojca, PISANSKI, Tomaž ĆIRKOVIĆ VELIČKOVIĆ, Tanja, ROUND, Adam, CARAZO, José María, MELERO, Roberto, JERALA, Roman. Design of coiled-coil protein origami cages that self-assemble in vitro and in vivo. Nature Biotechnology, 2017, 1-8
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