Departments

Slovenian NMR centre is a national facility offering access and expertise in NMR to users in academic and industrial institutions. The focus of our own research is on studies of structure and dynamics of biologically important (macro)molecules and their interactions.

1. Medved N., Cevec M., Javornik U., Lah J., Hadži S., Plavec J. Beyond Structure: Methylation Fine-Tunes Stability and Folding Kinetics of bcl2Mid G-Quadruplex. Angew. Chem. Int. Ed. 2025, 64(24), e202507544. https://doi.org/10.1002/anie.202507544
2. Aleksič S., Podbevšek P., Plavec J. Oxidative events in a double helix system promote the formation of kinetically trapped G-quadruplexes. Nucleic Acids Res. 2025, 53(6), gkaf260. https://doi.org/10.1093/nar/gkaf260
3. Takahashi S., Ghosh S., Trajkovski M., Ohyama T., Plavec J., Sugimoto N. Twisting tetraplex DNA: A strand dynamics regulating i-motif function in diverse molecular crowding environments. Nucleic Acids Res. 2025 53(12), gkaf500. https://doi.org/10.1093/nar/gkaf500
4. Sahoo B.R., Deng X., Wong E.L., Clark N., Yang H.J., Kovalenko A., et al. Visualization of liquid-liquid phase transitions using a tiny G-quadruplex binding protein. Nat. Commun. 2025, 16(1), 8578. https://doi.org/10.1038/s41467-025-63597-7
5. Ruggiero E., Marušič M., Zanin I., Peña Martinez Cristian D., Christ D., Plavec J., et al. The iMab antibody selectively binds to intramolecular and intermolecular i-motif structures. Nucleic Acids Res. 2025, 53(2), gkae1305. https://doi.org/10.1093/nar/gkae1305
6. Pevec M., Medved T., Kovačič M., Žerjav N., Imperl J., Plavec J., et al. Structural basis of G-quadruplex recognition by a camelid antibody fragment. Nucleic Acids Res. 2025, 53(10), gkaf453. https://doi.org/10.1093/nar/gkaf453
7. Trajkovski M., Pastore A., Plavec J. Dimeric structures of DNA ATTTC repeats promoted by divalent cations. Nucleic Acids Res. 2024, 52(4), 1591–601. https://doi.org/10.1093/nar/gkae052
8. Sahoo B.R., Kocman V., Clark N., Myers N., Deng X., Wong Ee L., et al. Protein G-quadruplex interactions and their effects on phase transitions and protein aggregation. Nucleic Acids Res. 2024, 52(8), 4702–22. https://doi.org/10.1093/nar/gkae229
9. Javornik U., Pérez-Romero A., López-Chamorro C., Smith R.M., Dobado J.A., Palacios O., et al. Unveiling the solution structure of a DNA duplex with continuous silver-modified Watson-Crick base pairs. Nat. Commun. 2024, 15(1), 7763. https://doi.org/10.1038/s41467-024-51876-8
10. Hadži S., Živič Z., Kovačič M., Zavrtanik U., Haeserts S., Charlier D., et al. Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae. Nat. Commun. 2024, 15(1), 3105. https://doi.org/10.1038/s41467-024-47296-3