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Determination of three-dimensional structures of biological macromolecules, analysis of 3D protein-ligand interactions at the atomic level
LaboratoryD11
EquipmentCryo-TEM sample preparation room with Vitrobot and other pieces of equipment for preparation of samples for cryo-TEM, cryo-transmission electron microscope (cryo-TEM) Glacios, computer servers for data storage, processing, refinement and model building using cryoT-EM.
FieldBiological and biochemical studies
PlatformAnalysis of biological samples
TechnicsSingle particle analysis, cryoelectron tomography, micro-crystal electron diffraction (MicroED). Storage, processing, refinement and construction of models using modern computer programs for cryo-TEM.
Contactizr. prof. dr. Marjetka Podobnik
marjetka.podobnik(at)ki.si
+386 1 4760 372
Description

Determination of 3D structures and interactions of proteins.

https://www.ki.si/en/departments/d11-department-of-molecular-biology-and-nanobiotechnology/research-activities/structure-and-mechanism-of-action-of-pathogenic-filamentous-plant-viruses/

https://www.ki.si/en/glacios/

https://www.ki.si/en/departments/d11-department-of-molecular-biology-and-nanobiotechnology/collaboration-with-industrial-and-other-partners/

 

 

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