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Departments

Research projects

ERC Grants

No.Project title (Acronym)PIPeriod
787115Molecular machines based on coiled-coil protein origami (MaCChines)Prof. dr. Roman Jerala2018-2024
899259Coiled-coil mediated exonuclease tethering technology for the enhancement of CRISPR gene editing (CCEdit)Prof. dr. Roman Jerala2020-2022

Horizon Europe and H2020 Grants

No.Project title (Acronym)PI / rolePeriod
101070817Closed-loop control of fungal materials (LoopOfFun)Prof. dr. Roman Jerala / Beneficiary2022-2027
101069496A Coordination and Support Action to prepare UNCAN.eu platform (4.UNCAN.eu)Prof. dr. Roman Jerala / Beneficiary2022-2023
899619

General-purpose virus-neutralizing engulfing shells with modular target-specificity (VIROFIGHT)

Prof. dr. Roman Jerala / Beneficiary2020-2024
820699

Fostering Synthetic Biology standardisation through international collaboration (BioRoboost)

Prof. dr. Roman Jerala / Beneficiary2018-2021
792305

CC-LEGO: robust protein blocks to build cages and layers (CC-LEGO)

Dr. Ajasja Ljubetič2018-2022
642157

Toll-Like Receptor 4 activation and function in diseases: an integrated chemical-biology approach (TOLLerant)

Prof. dr. Roman Jerala / Beneficiary2015-2018

Slovenian Research and Innovation Agency: Core programme and research projects

No.Programme/project titlePIPeriod
P4-0176

Synthetic biology and immunology

prof. dr. Roman Jerala2022-2027
N1-0323A random walker made of coiled helices and newly designed proteinsdr. Ajasja Ljubetič2022-2025
J7-4640Innovative CAR T cell cancer immunotherapy (CARRS)prof. dr. Roman Jerala2022-2025
J1-4406CC-Trigger: toehold mediated protein coiled-coil displacement to introduce kinetic control of protein assemblies and advanced multi-state devicesdr. Ajasja Ljubetič2022-2025
J1-4408Ultrasound signaling path with calcium-dependent positive feedback loop for chimeric antigen receptor activation for cancer immunotherapydr Mojca Benčina2022-2025
J4-4563Use of an improved CRISPR/Cas system for non-viral production of CAR-T cellsdr. Duško Lainšček2022-2025
Z3-4501

Induction of immunogenic cell death by a DNA sensor system that recognizes a genomic signature specific to cancer cells

dr. Taja Železnik Ramuta2022-2024
Z1-3193Optimized spliceosome-mediated RNA trans-splicing for cellular imaging and therapydr. Petra Sušjan2022-2024
V4-2038DNA vaccines and peptide inhibitors against SARS-CoV-2prof. dr. Roman Jerala2020-2022
Z4-2657Phosphorylation signaling pathway design in mammalian cellsdr. Tina Fink2020-2022
N1-0125Chemically enhanced coiled-coil protein origami: towards designed molecular machinesdr. Tamara Šmidlehner2020-2021
J4-1779Sonogenetics -ultrasound modulation of target gene expressiondr. Mojca Benčina2019-2022
J3-1746The functional role of cell death in different NLRP3 inflammasomeactivation pathways and its application for innovative cancer immunotherapydr. Iva Hafner Bratkovič2019-2022
J1-1711Designed protein origami based receptors: functionalized designed protein nanostructures for the recognition of the selected targetsdr. Helena Gradišar2019-2022
J3-9257Molecular mechanism of endogenous TLR4 agonist formation and its role in chronic inflammatory diseasesdr. Mateja Manček Keber2018-2021
J1-9173Design of a fast signaling and logic processing pathway based on orthogonal proteasesprof. dr. Roman Jerala2018-2021
J3-9268Cancer immunotherapy modulation by ultrasounddr. Mojca Benčina2018-2021
Z3-9260Intercellular transfer of the signaling complex by the extracellular vesicles secreted from the WM-associated MyD88 mutation carrying cellsdr. Vida Forstnerič2018-2020
Z3-9276Advanced nano-vaccines based on protein origami combining activators of innate and adaptive immune responsedr. Duško Lainšček2018-2020
N4-0080Optimizacija sinteznobioloških genskih vezij in reprogramiranja celic s pomočjo mikrofluidikeprof. dr. Roman Jerala2018-2021
J3-8196Intercellular transfer of the signaling complex by the extracellular vesicles secreted from the WM-associated MyD88 mutation carrying cellsdr. Mateja Manček Keber2017-2020
J3-7034Advanced nano-vaccines based on protein origami combining activators of innate and adaptive immune responsedr. Mojca Benčina2016-2018
N4-0037In vivo folding of designed proteinprof. dr. Roman Jerala2016-2018
J3-6784The molecular mechanism of single stranded DNA signaling via intracellular Toll-like receptor 9dr. Mojca Benčina2014-2017

Office of Naval Research (ONR) Grant

No.Project titlePIPeriod
N629092012090Sonogenetics: remote modulation of gene expression by ultrasoundProf. dr. Roman Jerala2020-2024
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