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Water-soluble cannabinoids with increased stability

Cannabinoids, such as CBD, have become an important global commodity. They have found their place in foods and beverages, cosmetics, and pharmaceuticals. The major problem of cannabinoids is their low water solubility, which largely restricts their use to to lipophilic mediums – mostly oil-based ones. Our technology unlocks aqueous solutions of cannabinoids and hemp resins with an increased stability and bioavailability.

Established technologies for increasing the water solubility of cannabinoids typically involve lipophilic molecules that allow for emulsification – the process of mixing two liquids that do not mix under normal conditions. Our technology takes a different approach unlocking true solutions that are clear, stable, exhibit no sedimentation, and are relatively inexpensive to prepare.

Our technology also makes crude cannabis resins soluble, significantly improving the usability of the technology. What is more, we have also observed that the technology increases the stability of relatively unstable acidic forms of cannabinoids, such as CBDA or CBGA. This is an important feature as these acidic forms are gaining market importance due to their unique properties.

Developed by: Department of Analytical Chemistry.

Technology readiness level: TRL5.

Status of intellectual property: Patent pending.

Cooperation opportunities: Joint development or intellectual property licensing.

2023 NICKI Support Recipient

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